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Enduro Sense - the future of bioproduction
Biological production puts a burden on the producing cells. In the conventional set-up this burden selects for the emergence of non-producing cells thereby preventing efficient bio-based production.
Our technology prevents declining production at scale by 'addicting' the cells to high production. We call this technology Enduro Sense and we offer optimized production strain performance – in any organism and at every scale.
What we offer
Enduro Sense
Enduro Sense is a simple genetic plugin that couples cell health with production – effectively making the cells addicted to the production of the desired product. This sustains fermentations over long time scales - and results in more high-producing cells.
Seamless integration
Enduro Sense can be integrated seamlessly into existing strains or can be used right from the drawing board, providing a flexible way scaling up high-production strains.
Benefits
Higher yield at scale
Get more out of existing strains by enriching spontaneous high producers in the fermentation population – increasing yield, titer and rate
Enduro Sense is free of antibiotic resistance genes, making handling more compliant, easier and safer
Antibiotic independence
Enable difficult processes
Production of complex or cellular inhibit products is eased when strain instability is overcome
Get started
Getting started with Enduro Sense is easy. Integration of the Enduro Sense plugins can be done on site without transfer of strains. Contact us today to learn how to obtain a starter kit.
EASY PARTNERSHIP MODEL
We offer flexible partner models that allow you to move fast forward and retain ownership.
FAST AND RESPONSIVE
We offer ultra-deep DNA sequencing of populations to profile escape routes of your strain designs
SAFETY ADAPTED TO YOU
We understand the importance of conforming to desired data safety regulations and regulatory requirements.
WHAT CAN ENDURO SENSE BE USED FOR?
Conventional bioproduction
EnduroSense
Using Enduro Sense, cells maintain their productive state longer, which creates a more homogenous population and higher yield.
Product independent
With our latest innovation (Enduro Sense 2.0), our proprietary platform technology is product independant, allowing us to produce any type of bioproducts.
Testimonials
Industrial Aquaporin production strain was improved by Enduro
Technology of Enduro has been demonstrated in the commercial process of Aquaporin A/S, a Danish manufacturer of sustainable water filter solutions. Enduro re-engineered the production strain. The new production strain performed at least 45% better in lab-scale tests.
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Error bars depict s.e.m. (n = 3).
In our constant R&D effort to deliver a more sustainable and efficient production process, we have been very satisfied working with Enduro Genetics.
Torsten Bak / Aquaporin A/S
Publications
Articles
Patents
pnas.org
Rugbjerg et al, 2018. Synthetic Product Addiction Extends the Productive Lifetime of Engineered Escherichia coli populations. PNAS
patents.google.com
WO2017055360A1 A System For Improved Fermentation Titers
Meet the Team
Christian Munch
CEO
Management
Board of Directors
Niels Peder Nielsen
Chair person
Thomas Videbæk
Board Member
Ejner Bech Jensen
Board Member
Niels Peder Nielsen
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Board member Noon Ventures and Mark Information, Senior advisor Bain & Company
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Previously deputy CEO of the Novo Nordisk Foundation and partner at Bain & Company
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MSc. MIT, Sloan School of Management
Thomas Videbæk
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Former COO Novozymes A/S and executive VP: Strategy and business transformation, Novozymes A/S
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Chairman of the Board of Protera
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Board Member Fenix Metals, Camlin Fine Sciences Ltd, Lyras
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Former board member Evolva AG
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MSc. Eng, PhD. Technical University of Denmark
Ejner Bech Jensen
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Former VP Novozymes and Novo Nordisk heading R&D within microbe, enzyme and biopharma biotechnology research and process dev.
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Former President of Novo Nordisk Biotech in California.
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MSc CheEng DTU
Peter Rugbjerg
CSO
Co-founder
Christian Munck
Co-founder
Christian Munck
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Co-founder, Enduro Genetics
Peter Rugbjerg
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CSO and Co-founder, Enduro Genetics
Christian Munch
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CEO, Enduro Genetics
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Previously SVP, New Business & Global Business Development, ALK-Abelló
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Former Director New Business, Novozymes
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MSc. Economics and Business administration, Copenhagen Business School
Scientists
Microbiologist
Synthetic Biologist
Fermentation biologist
Microbiologist
Synthetic Biologist
Laboratory Assistant
Synthetic Biologist
Student Lab Assistant
Open positions
We always invite unsolicited applications from molecular biology and fermentation scientists to jobs@endurogenetics.com.
If you are interested in an internship or a student project, contact us with an email subject containing "intern" or "student project".
Enduro
VISION
Relying on living organisms, bioproduction can be difficult to scale to large cultivation volumes while keeping titers high. By applying game-changing synthetic biology technology, we empower our partner companies to maximize performance of all cells cultivated from their production strains. By changing the desire of cells to produce, we increase competitiveness of current and future green bioproduction.
MISSION
Based in Copenhagen, Denmark, Enduro is an independent service and tech provider committed to improving large-scale fermentations.
LEARN MORE
Contact us at info@endurogenetics.com or +45 93 93 55 80.